Navarra promotes with 1.3 million a project for a new advanced therapy against cancer

The Department of Economic and Business Development has subsidized the project with 1,365,712.41 euros DESCARTHESwhich has developed a new advanced therapy for cancer treatmentwithin the call for aid for strategic R&D projects in 2019-2021.

The project has been presented this Friday by members of the consortium that has developed it, to the general director of Industry, Energy and Strategic Projects S4, Uxue Itoiz, at the Center for Applied Medical Research of the University of Navarra (CIMA).

The main objective of this project has been to develop a new advanced therapy for the treatment of cancer based on use of the patient’s own lymphocytes. “These lymphocytes are genetically modified in the laboratory so that they acquire an exceptional ability to recognize tumor cells and eliminate the tumor when they are injected back into the patient,” explains Dr. Juan José Lasarte, director of the Immunology and Immunotherapy Program at the Cima and project coordinator.

Thanks to this process, it has been possible to develop a platform that can serve to facilitate the incorporation of these therapies, based on CART cellsto the treatment of hematological cancers and solid tumors.

In addition, within the DESCARTHeS project, it has been possible to apply a complex methodology for the manufacture of cellular products. Finally, progress has been made in the development of two therapeutic products, one for the treatment of acute myeloid leukemia, and the other for the treatment of hepatocarcinoma.

The DESCARTHeS project has been developed within the framework of the call for Strategic Projects 2019-2021, within the GEMA (Genomics and Advanced Medicine) challenge. A consortium led by the CIMA University of Navarra (Foundation for Applied Medical Research) has participated in its preparation, with the participation of Navarrabiomed, the University Hospital of Navarra, the University Clinic of Navarra and the biotechnological company Recombina Biotech.

The results of this project will have continuity with the SOCRATHeS project, financed by the Government of Navarra in its call for Strategic Projects 2022


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